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Cenforce 150 mg, containing sildenafil citrate, is commonly used to treat erectile dysfunction by increasing blood flow to the penis. However, its interaction with antidepressants can pose significant health risks and should be approached with caution.

Key Interactions:
Serotonin Syndrome: Combining Cenforce 150 with certain antidepressants, especially SSRIs (Selective Serotonin Reuptake Inhibitors) and SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors), may increase the risk of serotonin syndrome. This is a potentially life-threatening condition characterized by high levels of serotonin, leading to symptoms like agitation, hallucinations, rapid heart rate, and fluctuating blood pressure​ (Damson Pharmacy)​.

Blood Pressure Changes: Cenforce can cause a drop in blood pressure. When taken with antidepressants, particularly those that also lower blood pressure (like tricyclic antidepressants), the combined effect can lead to hypotension (abnormally low blood pressure), causing dizziness, fainting, or even shock​ (GoodRxMedicine)​​ (GoodSexCare)​.

QT Interval Prolongation: Some antidepressants (e.g., certain SSRIs and tricyclics) can prolong the QT interval on an electrocardiogram, which can lead to serious heart rhythm disturbances. Sildenafil can exacerbate this effect, raising the risk of arrhythmias​ (Damson Pharmacy)​.

Common Side Effects:
Both Cenforce and antidepressants have overlapping side effects such as headaches, dizziness, and digestive issues. These can be more pronounced when the medications are taken together. Additionally, both can cause visual disturbances, further complicating their concurrent use​ (GoodRxMedicine)​​ (GoodSexCare)​.

Recommendations:
Medical Consultation: Always consult your healthcare provider before combining Cenforce with antidepressants. They can provide personalized advice based on your medical history and current medications.

Monitoring: Close monitoring for any adverse effects is crucial. If you experience symptoms like severe dizziness, heart palpitations, or signs of serotonin syndrome, seek medical attention immediately.

Dosage Adjustments: Your doctor may adjust the dosages of either medication to minimize the risk of interactions and side effects.

In summary, while Cenforce 150 mg can effectively treat erectile dysfunction, its interaction with antidepressants requires careful management and medical supervision to ensure safety and efficacy​ (Cenforce)​​ (GoodRxMedicine)​​ (Damson Pharmacy)​.