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Tadarise Pro 40 mg contains tadalafil, a medication used to treat erectile dysfunction (ED). It's important to be aware of contraindications—factors or conditions that make the use of a medication inadvisable or potentially dangerous—before taking Tadarise Pro 40 mg. Here are some contraindications to consider:

Nitrates: Tadalafil should not be taken with nitrates, such as nitroglycerin, isosorbide dinitrate, or isosorbide mononitrate. Concomitant use of tadalafil with nitrates can cause a sudden and significant drop in blood pressure, which can be dangerous and potentially life-threatening.

Alpha-blockers: Combining tadalafil with alpha-blockers used to treat high blood pressure or prostate enlargement can also cause a significant drop in blood pressure. Examples of alpha-blockers include doxazosin, prazosin, and terazosin. If you're taking alpha-blockers, your healthcare provider may adjust the dosage of tadalafil or recommend alternative treatments for ED.

Hypersensitivity: Individuals who have a known hypersensitivity or allergy to tadalafil or any other ingredients in Tadarise Pro 40 mg should not take this medication.

Heart conditions: Tadalafil can increase the risk of cardiovascular events in individuals with pre-existing heart conditions. It's important to consult with a healthcare provider before taking Tadarise Pro 40 mg if you have a history of heart disease, angina, arrhythmias, or other cardiovascular conditions.

Stroke: Tadalafil has been associated with an increased risk of stroke, particularly in individuals with underlying risk factors. If you have a history of stroke or are at an increased risk of stroke, it's essential to discuss the potential risks and benefits of tadalafil treatment with your healthcare provider.

Severe liver or kidney impairment: Tadalafil is primarily metabolized by the liver and excreted by the kidneys. Individuals with severe liver or kidney impairment may have reduced clearance of the medication, leading to increased blood levels and a higher risk of side effects. Dosage adjustments may be necessary in these individuals, or alternative treatments may be considered.

Certain eye conditions: Tadalafil has been associated with rare cases of non-arteritic anterior ischemic optic neuropathy (NAION), a condition that can cause sudden vision loss. Individuals with a history of NAION or other eye conditions such as retinitis pigmentosa should use tadalafil with caution and discuss the potential risks with their healthcare provider.

It's crucial to inform your healthcare provider about all medical conditions you have and all medications, supplements, and herbal products you're taking before starting treatment with Tadarise Pro 40 mg or any other medication containing tadalafil. Your healthcare provider can assess the potential risks and benefits and determine if tadalafil is appropriate for you based on your individual health status and medical history.