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Iverheal 12 mg is a medication that contains ivermectin, which is primarily used to treat certain parasitic infections in humans, such as onchocerciasis (river blindness) and strongyloidiasis. It is also used in the treatment of certain external parasites like head lice and skin conditions caused by parasitic infections.

Here are the main contraindications for taking Iverheal 12 mg:

Hypersensitivity: Individuals who have a known hypersensitivity or allergy to ivermectin or any of the ingredients in Iverheal should not take this medication. Allergic reactions can range from mild rash to severe symptoms such as difficulty breathing or swelling of the face, lips, tongue, or throat.

Concurrent Use with Strong CYP3A4 Inhibitors: Iverheal 12 Mg is metabolized by the liver enzyme CYP3A4. Concurrent use of strong CYP3A4 inhibitors can increase the levels of ivermectin in the blood, potentially leading to increased risk of side effects. Examples of strong CYP3A4 inhibitors include ketoconazole, itraconazole, clarithromycin, and ritonavir. If such medications are necessary, dosage adjustments may be required under medical supervision.

Neurological Conditions: Ivermectin can potentially worsen neurological conditions such as meningitis or conditions involving the central nervous system. Individuals with these conditions should use Iverheal with caution and under the close supervision of a healthcare provider.

Pregnancy and Breastfeeding: The safety of Iverheal 12 mg in pregnant or breastfeeding women has not been well established. It should be used during pregnancy or breastfeeding only if clearly needed and prescribed by a healthcare provider, weighing the potential benefits against the risks.

Children Under 15 kg: Iverheal 12 mg tablets are not recommended for use in children weighing less than 15 kg due to the potential for overdose or adverse effects. Other formulations and dosages should be used under medical supervision for younger children.

It's important to consult with a healthcare provider before taking Iverheal 12 mg to ensure it is safe and appropriate for you, especially if you have any underlying health conditions or are taking other medications. They can provide personalized advice based on your medical history and current health status.