forum.WMHelp.cz

[stephenbarkin]

Avaforce 50 mg contains avanafil, which is a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED) in men. Avanafil works by specifically targeting the enzyme PDE5, which is primarily found in the smooth muscle cells of the penis.
Relaxation of Blood Vessels: During sexual arousal, the body releases nitric oxide (NO) in the erectile tissue of the penis. Nitric oxide stimulates the production of cyclic guanosine monophosphate (cGMP), a chemical messenger that relaxes the smooth muscle cells of the penile blood vessels. This relaxation allows increased blood flow into the penis, leading to an erection.
Inhibition of PDE5: PDE5 is an enzyme that breaks down cGMP, which can prematurely end the erection by reducing blood flow to the penis. Avanafil in Avaforce 50 mg specifically inhibits PDE5, preventing it from breaking down cGMP. This allows cGMP to accumulate and remain active for a longer time, promoting sustained relaxation of the penile blood vessels and facilitating improved blood flow to the erectile tissue.
Erection Enhancement: By promoting increased blood flow to the penis, Avaforce 50 mg helps men with erectile dysfunction achieve and maintain an erection during sexual stimulation.