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Silagra 50 mg, which contains sildenafil, is primarily used to treat erectile dysfunction. It’s not typically recommended to combine it with certain antibiotics because some antibiotics can affect how Silagra 50 mg is metabolized in the body. Specifically, antibiotics that inhibit the cytochrome P450 enzymes (like CYP3A4) can increase sildenafil levels in the bloodstream, potentially leading to an increased risk of side effects. This can include symptoms like prolonged erection or low blood pressure. Always consult with a healthcare provider before combining medications to ensure safety and effectiveness.